The San Francisco 49ers (1-0) and Philadephia Eagles (1-0) will meet in Week 2 at Lincoln Financial Field in a game that could catapult the home team on a winning streak.
Updated at Monday at 5:30 p.m. ET.
Money line: 49ers -200 (bet $200 to win $100) | Eagles +160 (bet $100 to win $160)
Against the spread (ATS): 49ers -3.5, -115 (bet $115 to win $100) | Eagles +3.5, -107 (bet $107 to win $100)
Total (O/U): 50.5, Over -105 (bet $105 to win $100) | Under -115 (bet $115 to win $100)
Philadelphia will prepare for a dual-threat attack this week after the 49ers opened their season with a 41-33 victory at the Detroit, which saw the Lions score 16-points in the 4th quarter to blow up a 9.5-point spread.
Embattled quarterback Jimmy Garoppolo was 17-for-25 for 314 yards with 1 TD, while star rookie quarterback Trey Lance completed his only pass for a 5-yard TD.
Deebo Samuel powered the 49ers’ pass game with 9 receptions on 12 targets for 189 yards and a score.
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list.