The San Francisco 49ers (1-0) and Philadephia Eagles (1-0) will meet in Week 2 at Lincoln Financial Field in a game that could catapult the home team on a winning streak.
San Francisco is coming off a 41-33 win against Detroit in which Jimmy Garoppolo threw for 314 yards and a touchdown while the run game added 131 yards and two scores.
The 49ers blew a 24-point lead, but still are favored once again in Week 2, opening up at -3.5 against the Eagles.
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list.